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Title:

A new technology for stabilization of biomolecules in tissues for combined histological and molecular analyses.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Viertler, C; Groelz, D; Gundisch, S; Kashofer, K; Reischauer, B; Riegman, PH; Winther, R; Wyrich, R; Becker, KF; Oelmüller, U; Zatloukal, K
Abstract:
For accurate diagnosis, prediction of outcome, and selection of appropriate therapies, the molecular characterization of human diseases requires analysis of a broad spectrum of altered biomolecules, in addition to morphological features, in affected tissues such as tumors. In a high-throughput screening approach, we have developed the PAXgene Tissue System as a novel tissue stabilization technology. Comprehensive characterization of this technology in stabilized and paraffin-embedded human tissu...     »
Journal title abbreviation:
J Mol Diagn
Year:
2012
Journal volume:
14
Journal issue:
5
Pages contribution:
458-66
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jmoldx.2012.05.002
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22749745
Print-ISSN:
1525-1578
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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