Innate immunity's path to the Nobel Prize 2011 and beyond.

Titel:: Innate immunity's path to the Nobel Prize 2011 and beyond.
Dokumenttyp:: Historical Article; Journal Article
Autor(en):: Wagner, H
Abstract:: The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity. The Prize highlighted the initial discoveries of Toll's role in immunity in flies, Toll-like receptors in mammals, and the establishment of dendritic cells as the initiators of adaptive immunity. This historical Commentary focuses on the developments in our understanding of innate immunity.
Zeitschriftentitel:: Eur J Immunol
Jahr:: 2012
Band / Volume:: 42
Heft / Issue:: 5
Seitenangaben Beitrag:: 1089-92
Sprache:: eng
Volltext / DOI:: doi:10.1002/eji.201242404
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/22539282
Print-ISSN:: 0014-2980
TUM Einrichtung:: Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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