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Titel:

Innate immunity's path to the Nobel Prize 2011 and beyond.

Dokumenttyp:
Historical Article; Journal Article
Autor(en):
Wagner, H
Abstract:
The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity. The Prize highlighted the initial discoveries of Toll's role in immunity in flies, Toll-like receptors in mammals, and the establishment of dendritic cells as the initiators of adaptive immunity. This historical Commentary focuses on the developments in our understanding of innate immunity.
Zeitschriftentitel:
Eur J Immunol
Jahr:
2012
Band / Volume:
42
Heft / Issue:
5
Seitenangaben Beitrag:
1089-92
Sprache:
eng
Volltext / DOI:
doi:10.1002/eji.201242404
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22539282
Print-ISSN:
0014-2980
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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