Innate immunity's path to the Nobel Prize 2011 and beyond.

Title:: Innate immunity's path to the Nobel Prize 2011 and beyond.
Document type:: Historical Article; Journal Article
Author(s):: Wagner, H
Abstract:: The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity. The Prize highlighted the initial discoveries of Toll's role in immunity in flies, Toll-like receptors in mammals, and the establishment of dendritic cells as the initiators of adaptive immunity. This historical Commentary focuses on the developments in our understanding of innate immunity.
Journal title abbreviation:: Eur J Immunol
Year:: 2012
Journal volume:: 42
Journal issue:: 5
Pages contribution:: 1089-92
Language:: eng
Fulltext / DOI:: doi:10.1002/eji.201242404
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/22539282
Print-ISSN:: 0014-2980
TUM Institution:: Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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