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Titel:

Norovirus GII.4 and GII.7 capsid sequences undergo positive selection in chronically infected patients.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Hoffmann, D; Hutzenthaler, M; Seebach, J; Panning, M; Umgelter, A; Menzel, H; Protzer, U; Metzler, D
Abstract:
Norovirus has become an important cause for infectious gastroenteritis. Particularly genotype II.4 (GII.4) has been shown to spread rapidly and causes worldwide pandemics. Emerging new strains evade population immunity and lead to high norovirus prevalence. Chronic infections have been described recently and will become more prevalent with increasing numbers of immunocompromized patients. Here, we studied norovirus evolution in three chronically infected patients, two genotypes II.4 and one II.7...     »
Zeitschriftentitel:
Infect Genet Evol
Jahr:
2012
Band / Volume:
12
Heft / Issue:
2
Seitenangaben Beitrag:
461-6
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.meegid.2012.01.020
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22310302
Print-ISSN:
1567-1348
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Virologie
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