User: Guest  Login
Title:

Macrophages and their relevance in Human Immunodeficiency Virus Type I infection.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Koppensteiner, H; Brack-Werner, R; Schindler, M
Abstract:
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type, and a number of differences towards HIV-1 infection of CD4+ T cells have been described. There is a broad consensus that macrophages resist HIV-1 infection much better than CD4+ T cells. Among other reasons, this is due to the presence of the recently identified host cell restriction factor SamHD1, which is strongl...     »
Journal title abbreviation:
Retrovirology
Year:
2012
Journal volume:
9
Pages contribution:
82
Language:
eng
Fulltext / DOI:
doi:10.1186/1742-4690-9-82
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23035819
TUM Institution:
Institut für Virologie
 BibTeX