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Titel:

Macrophages and their relevance in Human Immunodeficiency Virus Type I infection.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Koppensteiner, H; Brack-Werner, R; Schindler, M
Abstract:
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type, and a number of differences towards HIV-1 infection of CD4+ T cells have been described. There is a broad consensus that macrophages resist HIV-1 infection much better than CD4+ T cells. Among other reasons, this is due to the presence of the recently identified host cell restriction factor SamHD1, which is strongl...     »
Zeitschriftentitel:
Retrovirology
Jahr:
2012
Band / Volume:
9
Seitenangaben Beitrag:
82
Sprache:
eng
Volltext / DOI:
doi:10.1186/1742-4690-9-82
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23035819
TUM Einrichtung:
Institut für Virologie
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