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Titel:

MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Elsner, M; Rauser, S; Maier, S; Schone, C; Balluff, B; Meding, S; Jung, G; Nipp, M; Sarioglu, H; Maccarrone, G; Aichler, M; Feuchtinger, A; Langer, R; Jütting, U; Feith, M; Küster, B; Ueffing, M; Zitzelsberger, H; Höfler, H; Walch, A
Abstract:
To characterize proteomic changes found in Barrett's adenocarcinoma and its premalignant stages, the proteomic profiles of histologically defined precursor and invasive carcinoma lesions were analyzed by MALDI imaging MS. For a primary proteomic screening, a discovery cohort of 38 fresh frozen Barrett's adenocarcinoma patient tissue samples was used. The goal was to find proteins that might be used as markers for monitoring cancer development as well as for predicting regional lymph node metasta...     »
Zeitschriftentitel:
J Proteomics
Jahr:
2012
Band / Volume:
75
Heft / Issue:
15
Seitenangaben Beitrag:
4693-704
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jprot.2012.02.012
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22365974
Print-ISSN:
1874-3919
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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