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Titel:

MALDI MS imaging as a powerful tool for investigating synovial tissue.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Kriegsmann, M; Seeley, EH; Schwarting, A; Kriegsmann, J; Otto, M; Thabe, H; Dierkes, B; Biehl, C; Sack, U; Wellmann, A; Kahaly, GJ; Schwamborn, K; Caprioli, RM
Abstract:
To identify and image protein biomarker candidates in the synovial tissue of patients with rheumatoid arthritis (RA) and patients with osteoarthritis (OA).A novel matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) technique was applied to the analysis of synovial tissue. Patients were classified according to the American College of Rheumatology (ACR) criteria for RA. Frozen sections were stained to obtain morphological data. Serial sections were desiccated, and s...     »
Zeitschriftentitel:
Scand J Rheumatol
Jahr:
2012
Band / Volume:
41
Heft / Issue:
4
Seitenangaben Beitrag:
305-9
Sprache:
eng
Volltext / DOI:
doi:10.3109/03009742.2011.647925
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22639849
Print-ISSN:
0300-9742
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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