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Title:

Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume.

Document type:
Comparative Study; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Carmichael, O; Xie, J; Fletcher, E; Singh, B; Decarli, C
Abstract:
Hippocampal injury in the Alzheimer's disease (AD) pathological process is region-specific and magnetic resonance imaging (MRI)-based measures of localized hippocampus (HP) atrophy are known to detect region-specific changes associated with clinical AD, but it is unclear whether these measures provide information that is independent of that already provided by measures of total HP volume. Therefore, this study assessed the strength of association between localized HP atrophy measures and AD-rela...     »
Journal title abbreviation:
Neurobiol Aging
Year:
2012
Journal volume:
33
Journal issue:
6
Pages contribution:
1124.e31-41
Language:
eng
Fulltext / DOI:
doi:10.1016/j.neurobiolaging.2011.08.016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22169204
Print-ISSN:
0197-4580
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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