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Title:

Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications.

Document type:
Journal Article
Author(s):
Wenzl, T; Wilkens, JJ
Abstract:
ABSTRACT:The increased resistance of hypoxic cells to ionizing radiation is usually believed to be the primary reason for treatment failure in tumors with oxygen-deficient areas. This oxygen effect can be expressed quantitatively by the oxygen enhancement ratio (OER). Here we investigate theoretically the dependence of the OER on the applied local dose for different types of ionizing irradiation and discuss its importance for clinical applications in radiotherapy for two scenarios: small dose va...     »
Journal title abbreviation:
Radiat Oncol
Year:
2011
Journal volume:
6
Pages contribution:
171
Language:
eng
Fulltext / DOI:
doi:10.1186/1748-717X-6-171
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22172079
Print-ISSN:
1748-717X
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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