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Titel:

Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications.

Dokumenttyp:
Journal Article
Autor(en):
Wenzl, T; Wilkens, JJ
Abstract:
ABSTRACT:The increased resistance of hypoxic cells to ionizing radiation is usually believed to be the primary reason for treatment failure in tumors with oxygen-deficient areas. This oxygen effect can be expressed quantitatively by the oxygen enhancement ratio (OER). Here we investigate theoretically the dependence of the OER on the applied local dose for different types of ionizing irradiation and discuss its importance for clinical applications in radiotherapy for two scenarios: small dose va...     »
Zeitschriftentitel:
Radiat Oncol
Jahr:
2011
Band / Volume:
6
Seitenangaben Beitrag:
171
Sprache:
eng
Volltext / DOI:
doi:10.1186/1748-717X-6-171
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22172079
Print-ISSN:
1748-717X
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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