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- Title:
Genetics of atopic dermatitis.
- Document type:
- Journal Article; Review
- Author(s):
- Bussmann, C; Weidinger, S; Novak, N
- Abstract:
- Atopic dermatitis (AD) is a multifactorial disease, with a strong genetic predisposition. Genome-wide studies as well as candidate gene studies revealed several susceptibility loci. Since the observation of a strong association of "loss of function" mutations in the filaggrin gene with AD, the epidermal barrier was rediscovered as important pathophysiological co-factor of this disease.
- Journal title abbreviation:
- J Dtsch Dermatol Ges
- Year:
- 2011
- Journal volume:
- 9
- Journal issue:
- 9
- Pages contribution:
- 670-6
- Language:
- eng
- Fulltext / DOI:
- doi:10.1111/j.1610-0387.2011.07656.x
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/21518425
- Print-ISSN:
- 1610-0379
- TUM Institution:
- Klinik und Poliklinik für Dermatologie und Allergologie
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