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Title:

Genetics of atopic dermatitis.

Document type:
Journal Article; Review
Author(s):
Bussmann, C; Weidinger, S; Novak, N
Abstract:
Atopic dermatitis (AD) is a multifactorial disease, with a strong genetic predisposition. Genome-wide studies as well as candidate gene studies revealed several susceptibility loci. Since the observation of a strong association of "loss of function" mutations in the filaggrin gene with AD, the epidermal barrier was rediscovered as important pathophysiological co-factor of this disease.
Journal title abbreviation:
J Dtsch Dermatol Ges
Year:
2011
Journal volume:
9
Journal issue:
9
Pages contribution:
670-6
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1610-0387.2011.07656.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21518425
Print-ISSN:
1610-0379
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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