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Title:

Mouse phenotyping.

Document type:
Journal Article; Review
Author(s):
Fuchs, H; Gailus-Durner, V; Adler, T; Aguilar-Pimentel, JA; Becker, L; Calzada-Wack, J; Da Silva-Buttkus, P; Neff, F; Götz, A; Hans, W; Hölter, SM; Horsch, M; Kastenmüller, G; Kemter, E; Lengger, C; Maier, H; Matloka, M; Möller, G; Naton, B; Prehn, C; Puk, O; Racz, I; Rathkolb, B; Römisch-Margl, W; Rozman, J; Wang-Sattler, R; Schrewe, A; Stöger, C; Tost, M; Adamski, J; Aigner, B; Beckers, J; Behrendt, H; Busch, DH; Esposito, I; Graw, J; Illig, T; Ivandic, B; Klingenspor, M; Klopstock, T; Kremmer...     »
Abstract:
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which mimic human conditions. Due to pleiotropic effects, one gene may have different functions in different organ systems or time points during developme...     »
Journal title abbreviation:
Methods
Year:
2011
Journal volume:
53
Journal issue:
2
Pages contribution:
120-35
Language:
eng
Fulltext / DOI:
doi:10.1016/j.ymeth.2010.08.006
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20708688
Print-ISSN:
1046-2023
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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