Benutzer: Gast  Login
Titel:

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Moretti, A; Bellin, M; Jung, CB; Thies, TM; Takashima, Y; Bernshausen, A; Schiemann, M; Fischer, S; Moosmang, S; Smith, AG; Lam, JT; Laugwitz, KL
Abstract:
Ectopic expression of defined sets of genetic factors can reprogram somatic cells to create induced pluripotent stem (iPS) cells. The capacity to direct human iPS cells to specific differentiated lineages and to their progenitor populations can be used for disease modeling, drug discovery, and eventually autologous cell replacement therapies. During mouse cardiogenesis, the major lineages of the mature heart, cardiomyocytes, smooth muscle cells, and endothelial cells arise from a common, multipo...     »
Zeitschriftentitel:
FASEB J
Jahr:
2010
Band / Volume:
24
Heft / Issue:
3
Seitenangaben Beitrag:
700-11
Sprache:
eng
Volltext / DOI:
doi:10.1096/fj.09-139477
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19850773
Print-ISSN:
0892-6638
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Institut für Pharmakologie und Toxikologie
 BibTeX