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Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Mueller, K; Michel, K; Krueger, D; Demir, IE; Ceyhan, GO; Zeller, F; Kreis, ME; Schemann, M 
Title:
Activity of protease-activated receptors in the human submucous plexus. 
Abstract:
Protease-activated receptors (PARs) are expressed in the enteric nervous system. Excessive release of proteases has been reported in functional and inflammatory bowel diseases. Studies in several animal models indicate the involvement of neural PARs. We studied the actions of different PAR-activating peptides (AP) in the human submucous plexus and performed comparative studies in guinea pig submucous neurons.We used voltage- and calcium-sensitive dye recordings to study the effects of PAR1-AP, P...    »
 
Journal title abbreviation:
Gastroenterology 
Year:
2011 
Journal volume:
141 
Journal issue:
Pages contribution:
2088-2097.e1 
Language:
eng 
Print-ISSN:
0016-5085 
TUM Institution:
Chirurgische Klinik und Poliklinik