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Titel:

Activity of protease-activated receptors in the human submucous plexus.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Mueller, K; Michel, K; Krueger, D; Demir, IE; Ceyhan, GO; Zeller, F; Kreis, ME; Schemann, M
Abstract:
Protease-activated receptors (PARs) are expressed in the enteric nervous system. Excessive release of proteases has been reported in functional and inflammatory bowel diseases. Studies in several animal models indicate the involvement of neural PARs. We studied the actions of different PAR-activating peptides (AP) in the human submucous plexus and performed comparative studies in guinea pig submucous neurons.We used voltage- and calcium-sensitive dye recordings to study the effects of PAR1-AP, P...     »
Zeitschriftentitel:
Gastroenterology
Jahr:
2011
Band / Volume:
141
Heft / Issue:
6
Seitenangaben Beitrag:
2088-2097.e1
Sprache:
eng
Volltext / DOI:
doi:10.1053/j.gastro.2011.08.034
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21875497
Print-ISSN:
0016-5085
TUM Einrichtung:
Chirurgische Klinik und Poliklinik
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