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Titel:

Neighbor of punc E11, a novel oncofetal marker for hepatocellular carcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Marquardt, JU; Quasdorff, M; Varnholt, H; Curth, HM; Mesghenna, S; Protzer, U; Goeser, T; Nierhoff, D
Abstract:
Hepatocellular carcinoma (HCC) is the 5th common malignancy worldwide, but established markers fail to detect up to one third of HCC. We have recently identified Neighbor of Punc E11 (Nope) as a surface marker for murine fetal liver stem cells. Similar to commonly used HCC markers such as ?-Fetoprotein (Afp) and Glypican-3 (Gpc-3), we here establish Nope as an oncofetal marker of murine and human HCC and investigate its specific expression in hepatoma cell lines and primary HCC. Murine and human...     »
Zeitschriftentitel:
Int J Cancer
Jahr:
2011
Band / Volume:
128
Heft / Issue:
10
Seitenangaben Beitrag:
2353-63
Sprache:
eng
Volltext / DOI:
doi:10.1002/ijc.25567
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20658536
Print-ISSN:
0020-7136
TUM Einrichtung:
Institut für Virologie
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