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Titel:

Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Vincendeau, M; Kramer, S; Hadian, K; Rothenaigner, I; Bell, J; Hauck, SM; Bickel, C; Nagel, D; Kremmer, E; Werner, T; Leib-Mösch, C; Brack-Werner, R
Abstract:
In human astrocytes, restriction of HIV replication involves inhibition of HIV Rev activity. We previously identified a Rev-interacting human protein fragment (16.4.1) that can reduce Rev activity. The 16.4.1 sequence is contained in a group of highly similar host cell proteins, which we call the Risp family. Here we investigate whether the Risp family is connected to HIV replication in astrocytes.Cell/tissue lysates were analyzed for Risp expression by western blot with various anti-Risp antibo...     »
Zeitschriftentitel:
AIDS
Jahr:
2010
Band / Volume:
24
Heft / Issue:
16
Seitenangaben Beitrag:
2433-42
Sprache:
eng
Volltext / DOI:
doi:10.1097/QAD.0b013e32833e8758
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20827171
Print-ISSN:
0269-9370
TUM Einrichtung:
Institut für Virologie
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