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Titel:

Control of hepatitis B virus at the level of transcription.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Quasdorff, M; Protzer, U
Abstract:
Hepatitis B virus (HBV) is tightly controlled by a number of noncytotoxic mechanisms. This control occurs within the host hepatocyte at different steps of the HBV replication cycle. HBV persists by establishing a nuclear minichromosome, HBV cccDNA, serving as a transcription template for the viral pregenome and viral mRNAs. Nucleoside/nucleotide analogues widely used for antiviral therapy as well as most antiviral cytokines act at steps after transcription of HBV RNAs and thus can control virus...     »
Zeitschriftentitel:
J Viral Hepat
Jahr:
2010
Band / Volume:
17
Heft / Issue:
8
Seitenangaben Beitrag:
527-36
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1365-2893.2010.01315.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20546497
Print-ISSN:
1352-0504
TUM Einrichtung:
Institut für Virologie
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