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Titel:

Apoptosis of hepatitis B virus-infected hepatocytes prevents release of infectious virus.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Arzberger, S; Hösel, M; Protzer, U
Abstract:
Apoptosis of infected cells is critically involved in antiviral defense. Apoptosis, however, may also support the release and spread of viruses. Although the elimination of infected hepatocytes is required to combat hepatitis B virus (HBV) infection, it is still unknown which consequences hepatocyte apoptosis has for the virus and whether or not it is advantageous to the virus. To study this, we designed a cell culture model consisting of both HBV-producing cell lines and primary human hepatocyt...     »
Zeitschriftentitel:
J Virol
Jahr:
2010
Band / Volume:
84
Heft / Issue:
22
Seitenangaben Beitrag:
11994-2001
Sprache:
eng
Volltext / DOI:
doi:10.1128/JVI.00653-10
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20719950
Print-ISSN:
0022-538X
TUM Einrichtung:
Institut für Virologie
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