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Titel:

Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Meggendorfer, M; Weierich, C; Wolff, H; Brack-Werner, R; Cremer, T
Abstract:
A new experimental approach was designed to test different predictions of current models of the nuclear architecture with respect to the topography of transcription. We constructed a plasmid, termed pIndi, which carries a reporter gene coding for a red cytoplasmic fluorescent reporter protein. Transcription of the reporter gene is regulated by the inducible promoter of the human immunodeficiency virus (HIV) and is strongly dependent on the HIV-1 Tat protein. Expressing the red fluorescent report...     »
Zeitschriftentitel:
Chromosome Res
Jahr:
2010
Band / Volume:
18
Heft / Issue:
4
Seitenangaben Beitrag:
401-17
Sprache:
eng
Volltext / DOI:
doi:10.1007/s10577-010-9133-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20532610
Print-ISSN:
0967-3849
TUM Einrichtung:
Institut für Virologie
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