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Titel:

New vistas on TLR9 activation.

Dokumenttyp:
Comment; Journal Article
Autor(en):
Wagner, H
Abstract:
Together with other reports, evidence published in this issue of the European Journal of Immunology by Avalos and Ploegh (Eur. J. Immunol. 2011. 41: 2820-2827) implies that trafficking of TLR9 from the ER to endolysosomal compartments, which is aided by the transmembrane UNC93B1 ER protein, is followed by proteolytic cleavage of the TLR9 ectodomain (TLR9ecto). Furthermore, Avalos and Ploegh elegantly show that RAW 264.7 macrophages stably expressing tagged TLR9 display significant amounts of cle...     »
Zeitschriftentitel:
Eur J Immunol
Jahr:
2011
Band / Volume:
41
Heft / Issue:
10
Seitenangaben Beitrag:
2814-6
Sprache:
eng
Volltext / DOI:
doi:10.1002/eji.201142056
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21953639
Print-ISSN:
0014-2980
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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