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Title:

Steroid binding properties of the 2nd WHO International Standard for sex hormone-binding globulin.

Document type:
Journal Article
Author(s):
Thaler, M; Müller, C; Schlichtiger, A; Gründler, K; Moore, M; Luppa, PB
Abstract:
Stocks of 95/560, the 1st International Standard for sex hormone-binding globulin (SHBG), are running out, and 08/266 has been prepared as a replacement. We compared the steroid binding capacities of 95/560 and 08/266.95/560 and 08/266 stored at -20 °C, and accelerated thermal degradation samples of 08/266 were subjected to gelfiltration. Binding of the SHBG-containing fractions to a dihydrotestosterone derivative was then investigated using a surface plasmon resonance biosensor. The SHBG conten...     »
Journal title abbreviation:
Clin Chem Lab Med
Year:
2011
Journal volume:
49
Journal issue:
5
Pages contribution:
869-72
Language:
eng
Fulltext / DOI:
doi:10.1515/CCLM.2011.146
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21345159
Print-ISSN:
1434-6621
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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