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Document type:
Journal Article; Review; Article 
Author(s):
Bonifacio, E; Ziegler, AG 
Title:
Advances in the prediction and natural history of type 1 diabetes. 
Abstract:
Type 1 diabetes (T1D) has the hallmark characteristics of autoimmunity superimposed on genetic susceptibility. Both genes (HLA) and immune markers (autoantibodies) have been validated as predictive markers of the subsequent development of the disease in higher-risk relatives and the lower-risk general population. Over the last three decades, using a combination of genes, immune, and metabolic markers, clinicians are now able to quantify an individual's disease risk from 1 in 100,000 to more than...    »
 
Journal title abbreviation:
Endocrinol Metab Clin North Am 
Year:
2010 
Journal volume:
39 
Journal issue:
Pages contribution:
513-25 
Language:
eng 
Print-ISSN:
0889-8529 
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin