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Title:

Peripheral nerve reconstruction with collagen tubes filled with denatured autologous muscle tissue in the rat model.

Document type:
Comparative Study; Journal Article
Author(s):
Dornseifer, U; Fichter, AM; Leichtle, S; Wilson, A; Rupp, A; Rodenacker, K; Ninkovic, M; Biemer, E; Machens, HG; Matiasek, K; Papadopulos, NA
Abstract:
Conventional nerve conduits lack cellular and extracellular guidance structures critical for bridging larger defects. In this study, an exogenous matrix for axonal regeneration was provided by pretreated muscle tissue. In 24 rats, 14-mm sciatic nerve segments were resected and surgically reconstructed using one of the following methods: autograft (AG); bovine type I collagen conduit; (MDM) collagen tube filled with modified denatured autologous muscle tissue. For 8 weeks, functional regenerati...     »
Journal title abbreviation:
Microsurgery
Year:
2011
Journal volume:
31
Journal issue:
8
Pages contribution:
632-41
Language:
eng
Fulltext / DOI:
doi:10.1002/micr.20926
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22072584
Print-ISSN:
0738-1085
TUM Institution:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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