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Title:

Apoptosis: embedded in membranes.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Bogner, C; Leber, B; Andrews, DW
Abstract:
Many different signals for cell death converge on outer mitochondrial membrane permeabilization, a process controlled by the Bcl-2 family of proteins. Recent structural and biochemical analyses emphasize that key regulatory interactions between different classes of Bcl-2 family members occur at and in intracellular membranes, and insertion into membranes causes functionally important conformational changes in the proteins.
Journal title abbreviation:
Curr Opin Cell Biol
Year:
2010
Journal volume:
22
Journal issue:
6
Pages contribution:
845-51
Language:
eng
Fulltext / DOI:
doi:10.1016/j.ceb.2010.08.002
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20801011
Print-ISSN:
0955-0674
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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