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Titel:

The German Cancer Consortium (DKTK) multi-center prospective phase 1/2 68Ga-PSMA-11 PET-imaging trial in newly-diagnosed high-risk prostate cancer: Safety and diagnostic accuracy compared to histopathology and their impact on patient management.

Dokumenttyp:
Journal Article; Multicenter Study; Clinical Trial, Phase II; Clinical Trial, Phase I; Comparative Study
Autor(en):
Giesel, Frederik L; Koerber, Stefan A; Hadaschik, Boris; Kiefer, Selina; Schwarzenboeck, Sarah; Rahbar, Kambiz; Derlin, Thorsten; Grott, Christoph A; Heck, Matthias; Jilg, Cordula; Meyer, Philipp T; Ruf, Juri; Schmidt, Karl; Kotzerke, Joerg; la Fougère, Christian; Reischl, Gerald; Virgolini, Irene; Herrmann, Ken; Burger, Irene A; Lorenzini, Theo; Werner, Martin; Stenzinger, Albrecht; Schwamborn, Kristina; Radtke, Jan Philipp; Hohenfellner, Markus; Debus, Juergen; Weber, Wolfgang A; Haberkorn, Uw...     »
Abstract:
PURPOSE: Clinically accurate detection of prostate cancer (PCa) metastases is crucial for management of high-risk PCa patients scheduled for radical prostatectomy. We determine the safety and diagnostic accuracy of pre-operative 68Ga-PSMA-11 PET/CT imaging in newly diagnosed high-risk PCa and assess its impact on patient management. METHODS: Investigator-initiated prospective multi-center multinational single-arm open-label phase 1/2 imaging trial (EuRadCT 2016-001815-19). Patients with high-ris...     »
Zeitschriftentitel:
Eur J Nucl Med Mol Imaging
Jahr:
2026
Band / Volume:
53
Heft / Issue:
5
Seitenangaben Beitrag:
2994-3006
Volltext / DOI:
doi:10.1007/s00259-025-07540-4
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/41240091
Print-ISSN:
1619-7070
TUM Einrichtung:
1413; 1473; 170; Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)
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