Obesity is a chronic inflammatory status with increased blood levels of pro-inflammatory substances. We showed that modest weight loss (5-10 %) is required to improve serum levels of total and HMW adiponectin (+0.9 and + 0.5µg/ml, respectively) and MCP-1 (-10.8pg/ml), whereas the levels of other adipokines,
e.g. IP-10, RANTES and PGRN seem to be independent of weight loss. The improvement of metabolic risk factors associated with weight loss may favor a reduced risk of developing metabolic diseases.
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Obesity is a chronic inflammatory status with increased blood levels of pro-inflammatory substances. We showed that modest weight loss (5-10 %) is required to improve serum levels of total and HMW adiponectin (+0.9 and + 0.5µg/ml, respectively) and MCP-1 (-10.8pg/ml), whereas the levels of other adipokines,
e.g. IP-10, RANTES and PGRN seem to be independent of weight loss. The improvement of metabolic risk factors associated with weight loss may favor a reduced risk of developing metabolic disea...
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