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Title:

An in vitro characterization study of new near infrared dyes for molecular imaging.

Document type:
journal article
Author(s):
Pauli, J; Vag, T; Haag, R; Spieles, M; Wenzel, M; Kaiser, WA; Resch-Genger, U; Hilger, I
Abstract:
The spectroscopic properties, stability, and cytotoxicity of series of cyanine labels, the dyes DY-681, DY-731, DY-751, and DY-776, were studied to identify new tools for in vivo fluorescence imaging and to find substitutes for DY-676 recently used by us as fluorescent label in a target-specific probe directed against carcinoembryonic antigen (CEA). This probe enables the selective monitoring of CEA-expressing tumor cells in mice, yet displays only a low fluorescence quantum yield and thus, a no...     »
Journal title abbreviation:
Eur J Med Chem
Year:
2009
Journal volume:
44
Journal issue:
9
Pages contribution:
3496-503
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19269067
Print-ISSN:
0223-5234
TUM Institution:
Röntgendiagnostik
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