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Dokumenttyp:
journal article
Autor(en):
Zhang, D; Feng, XY; Henning, TD; Wen, L; Lu, WY; Pan, H; Wu, X; Zou, LG
Titel:
MR imaging of tumor angiogenesis using sterically stabilized Gd-DTPA liposomes targeted to CD105.
Abstract:
AIM: To depict tumor angiogenesis via the expression of CD105 in tumor-bearing rats using Gd-DTPA liposomes targeted to CD105 (CD105-Gd-SLs) on MR imaging. MATERIALS AND METHODS: Three Gd-DTPA liposomal nanoparticles were prepared in our trial: liposomes entrapping Gd-DTPA (Gd-SLs), Gd-SLs conjugated to immunoglobulins (IgG-Gd-SLs) and CD105-Gd-SLs. Forty glioma-bearing rats were randomized into four groups: (a) Gd-DTPA; (b) Gd-SLs; (c) IgG-Gd-SLs; (d) CD105-Gd-SLs. Axial T1WI MRI images were...     »
Zeitschriftentitel:
Eur J Radiol
Jahr:
2009
Band / Volume:
70
Heft / Issue:
1
Seitenangaben Beitrag:
180-9
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18541399
Print-ISSN:
0720-048X
TUM Einrichtung:
Röntgendiagnostik
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