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Title:

Genome-wide linkage analysis of serum creatinine in three isolated European populations.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Pattaro, C; Aulchenko, YS; Isaacs, A; Vitart, V; Hayward, C; Franklin, CS; Polasek, O; Kolcic, I; Biloglav, Z; Campbell, S; Hastie, N; Lauc, G; Meitinger, T; Oostra, BA; Gyllensten, U; Wilson, JF; Pichler, I; Hicks, AA; Campbell, H; Wright, AF; Rudan, I; van Duijn, CM; Riegler, P; Marroni, F; Pramstaller, PP
Abstract:
There is increasing evidence for a role of genetic predisposition in the etiology of kidney disease, but linkage scans have been poorly replicated. Here we performed a genome-wide linkage analysis of serum creatinine on 2859 individuals from isolated villages in South Tyrol (Italy), Rucphen (The Netherlands) and Vis Island (Croatia), populations that have been stable and permanently resident in their region. Linkage of serum creatinine levels to loci on chromosomes 7p14, 9p21, 11p15, 15q15-21, 1...     »
Journal title abbreviation:
Kidney Int
Year:
2009
Journal volume:
76
Journal issue:
3
Pages contribution:
297-306
Language:
eng
Fulltext / DOI:
doi:10.1038/ki.2009.135
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19387472
Print-ISSN:
0085-2538
TUM Institution:
Institut für Humangenetik
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