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Title:

Effects of Early Clozapine Treatment on Remission Rates in Acute Schizophrenia (The EARLY Trial): Protocol of a Randomized-Controlled Multicentric Trial.

Document type:
Article; Clinical Trial Protocol; Journal Article
Author(s):
Wagner, Elias; Strube, Wolfgang; Görlitz, Thomas; Aksar, Aslihan; Bauer, Ingrid; Campana, Mattia; Moussiopoulou, Joanna; Hapfelmeier, Alexander; Wagner, Petra; Egert-Schwender, Silvia; Bittner, Robert; Eckstein, Kathrin; Nenadić, Igor; Kircher, Tilo; Langguth, Berthold; Meisenzahl, Eva; Lambert, Martin; Neff, Sigrid; Malchow, Berend; Falkai, Peter; Hirjak, Dusan; Böttcher, Kent-Tjorben; Meyer-Lindenberg, Andreas; Blankenstein, Christiane; Leucht, Stefan; Hasan, Alkomiet
Abstract:
BACKGROUND: Quick symptomatic remission after the onset of psychotic symptoms is critical in schizophrenia treatment, determining the subsequent disease course and recovery. In this context, only every second patient with acute schizophrenia achieves symptomatic remission within three months of initiating antipsychotic treatment. The potential indication extension of clozapine-the most effective antipsychotic-to be introduced at an earlier stage (before treatment-resistance) is supported by seve...     »
Journal title abbreviation:
Pharmacopsychiatry
Year:
2023
Journal volume:
56
Journal issue:
5
Pages contribution:
169-181
Fulltext / DOI:
doi:10.1055/a-2110-4259
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37506738
Print-ISSN:
0176-3679
TUM Institution:
Lehrstuhl für Allgemeinmedizin (Prof. Schneider); Lehrstuhl für Medizinische Informatik (Prof. Boeker)
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