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Titel:

Expression and function of the coxsackie and adenovirus receptor in Barrett's esophagus and associated neoplasia.

Dokumenttyp:
Journal Article
Autor(en):
Anders, M; Rösch, T; Küster, K; Becker, I; Höfler, H; Stein, HJ; Meining, A; Wiedenmann, B; Sarbia, M
Abstract:
Cell surface presence of the coxsackie and adenovirus receptor (CAR) is considered a crucial prerequisite for the uptake of attenuated adenovirus. In cancers, however, a frequent loss of CAR has been noted potentially hampering the success of adenovirus-based therapy. In esophageal Barrett's carcinomas and its precursor lesions CAR presence has not been systematically determined yet. Immunohistochemical assessment in tissue specimens of 111 patients revealed CAR-positivity in all cases of Barret...     »
Zeitschriftentitel:
Cancer Gene Ther
Jahr:
2009
Band / Volume:
16
Heft / Issue:
6
Seitenangaben Beitrag:
508-15
Sprache:
eng
Volltext / DOI:
doi:10.1038/cgt.2008.103
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19132065
Print-ISSN:
0929-1903
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Allgemeine Pathologie und Pathologische Anatomie
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