User: Guest  Login
Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Altomonte, J; Wu, L; Meseck, M; Chen, L; Ebert, O; García-Sastre, A; Fallon, J; Mandeli, J; Woo, SL
Title:
Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells.
Abstract:
Recombinant oncolytic viruses represent a promising alternative option for the treatment of malignant cancers. We have reported earlier the safety and efficacy of recombinant vesicular stomatitis virus (VSV) vectors in a rat model of hepatocellular carcinoma (HCC). However, the full potential of VSV therapy is limited by a sudden decline in intratumoral virus replication observed early after viral administration, a phenomenon that coincides with an accumulation of inflammatory cells within infec...     »
Journal title abbreviation:
Cancer Gene Ther
Year:
2009
Journal volume:
16
Journal issue:
3
Pages contribution:
266-78
Language:
eng
Fulltext / DOI:
doi:10.1038/cgt.2008.74
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18846115
Print-ISSN:
0929-1903
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie)
 BibTeX