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Title:

A randomized multicentre phase II trial comparing adjuvant therapy in patients with interferon alpha-2b and 5-FU alone or in combination with either external radiation treatment and cisplatin (CapRI) or radiation alone regarding event-free survival - CapR

Document type:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; nicht gelistet
Author(s):
Märten, A; Schmidt, J; Ose, J; Harig, S; Abel, U; Münter, MW; Jäger, D; Friess, H; Mayerle, J; Adler, G; Seufferlein, T; Gress, T; Schmid, R; Büchler, MW
Abstract:
The 5-year survival of patients with resected pancreatic adenocarcinoma is still unsatisfying. The ESPAC-1 and the CONKO 001 trial proofed that adjuvant chemotherapy improves 5-year survival significantly from approximately 14% to 21%. In parallel, investigators from the Virginia Mason Clinic reported a 5-year survival rate of 55% in a phase II trial evaluating a combination of adjuvant chemotherapy, immunotherapy and external beam radiation (CapRI-scheme). Two other groups confirmed in phase II...     »
Journal title abbreviation:
BMC Cancer
Year:
2009
Journal volume:
9
Pages contribution:
160
Language:
eng
Fulltext / DOI:
doi:10.1186/1471-2407-9-160
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19470159
TUM Institution:
Chirurgische Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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