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Titel:

Characterization of choline uptake in prostate cancer cells following bicalutamide and docetaxel treatment.

Dokumenttyp:
Journal Article; Article
Autor(en):
Müller, SA; Holzapfel, K; Seidl, C; Treiber, U; Krause, BJ; Senekowitsch-Schmidtke, R
Abstract:
PURPOSE: Choline derivatives labelled with positron emitters are successfully used for PET imaging of prostate cancer patients. Since little is known about uptake mechanisms, the aim of this study was to characterize choline uptake in prostate cancer cells, also following anti-androgen treatment or chemotherapy. METHODS: Choline uptake in prostate cancer cells (LNCaP, PC-3) and Michaelis-Menten kinetics were analysed using different concentrations of (3)H-choline via liquid scintillation countin...     »
Zeitschriftentitel:
Eur J Nucl Med Mol Imaging
Jahr:
2009
Band / Volume:
36
Heft / Issue:
9
Seitenangaben Beitrag:
1434-42
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00259-009-1117-x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19352653
Print-ISSN:
1619-7070
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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