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Titel:

Iron Oxide Nanoparticles with Supramolecular Ureido-Pyrimidinone Coating for Antimicrobial Peptide Delivery

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Turrina C; Cookman J; Bellan R; Song J; Paar M; Dankers P Y W; Berensmeier S; Schwaminger, S P
Abstract:
Antimicrobial peptides (AMPs) can kill bacteria by disrupting their cytoplasmic membrane, which reduces the tendency of antibacterial resistance compared to conventional antibiotics. Their possible toxicity to human cells, however, limits their applicability. The combination of magnetically controlled drug delivery and supramolecular engineering can help to reduce the dosage of AMPs, control the delivery, and improve their cytocompatibility. Lasioglossin III (LL) is a natural AMP form bee venom...     »
Stichworte:
iron oxide nanoparticles; ureido-pyrimidinone; supramolecular system; antimicrobial peptide; intracellular delivery; cytocompatibility
Zeitschriftentitel:
International Journal of Molecular Sciences
Jahr:
2023
Band / Volume:
24
Heft / Issue:
19
Seitenangaben Beitrag:
14649
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.3390/ijms241914649
WWW:
%20https%3A//doi.org/10.3390/ijms241914649%20
Verlag / Institution:
MDPI AG
E-ISSN:
1422-0067
Publikationsdatum:
27.09.2023
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