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Titel:

How to design a low-cost pilot scale magnetic bioseparation process for protein separation from complex mixtures using in-line process analytics

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Krolitzki E; Steck S; Nazifi A; Abt M; Schwaminger SP; Berensmeier S
Abstract:
Magnetic separation is a powerful tool for the integrated capture and purification of biomolecules and cells directly from complex feed media without the need for prior clarification and without the risk of equipment blockage. In this study, we equipped a commercially available rotor–stator high-gradient magnetic separator (RS-HGMS) with in-line analytics of hygienic design (absorbance, conductivity, pH, and flow) and used it for a systematic characterization of the equipment. By combining parti...     »
Stichworte:
Magnetic separation; Bioseparation; Protein purification; Capture; Iron oxide nanoparticles; Lactoferrin
Zeitschriftentitel:
Separation and Purification Technology
Jahr:
2023
Band / Volume:
323
Jahr / Monat:
2023-10
Seitenangaben Beitrag:
124429
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1016/j.seppur.2023.124429
WWW:
https://www.sciencedirect.com/science/article/pii/S1383586623013370
Verlag / Institution:
Elsevier BV
Print-ISSN:
13835866
E-ISSN:
1383-5866
Impact Factor:
9.1
Angenommen (von Zeitschrift):
24.06.2023
Publikationsdatum:
27.06.2023
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