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Title:

Iron Oxide Nanoparticles with Supramolecular Ureido-Pyrimidinone Coating for Antimicrobial Peptide Delivery

Document type:
Zeitschriftenaufsatz
Author(s):
Turrina C; Cookman J; Bellan R; Song J; Paar M; Dankers P Y W; Berensmeier S; Schwaminger, S P
Abstract:
Antimicrobial peptides (AMPs) can kill bacteria by disrupting their cytoplasmic membrane, which reduces the tendency of antibacterial resistance compared to conventional antibiotics. Their possible toxicity to human cells, however, limits their applicability. The combination of magnetically controlled drug delivery and supramolecular engineering can help to reduce the dosage of AMPs, control the delivery, and improve their cytocompatibility. Lasioglossin III (LL) is a natural AMP form bee venom...     »
Keywords:
iron oxide nanoparticles; ureido-pyrimidinone; supramolecular system; antimicrobial peptide; intracellular delivery; cytocompatibility
Journal title:
International Journal of Molecular Sciences
Year:
2023
Journal volume:
24
Journal issue:
19
Pages contribution:
14649
Covered by:
Scopus
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.3390/ijms241914649
WWW:
%20https%3A//doi.org/10.3390/ijms241914649%20
Publisher:
MDPI AG
E-ISSN:
1422-0067
Date of publication:
27.09.2023
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