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Titel:

Indirect MR-arthrography in osteochondral autograft and crushed bone graft with a collagen membrane--correlation with histology.

Dokumenttyp:
Journal Article
Autor(en):
Streitparth, F; Schöttle, P; Schell, H; Lehmkuhl, L; Madej, T; Wieners, G; Duda, GN; Schröder, RJ
Abstract:
OBJECTIVE: To analyze the spectrum of findings in indirect MR-arthrography following osteochondral autograft transfer system (OATS) and crushed bone graft using a magnetic resonance imaging (MRI) scoring and grading system in relation to histology as the standard of reference. MATERIALS AND METHODS: Iatrogenic lesions were set at ovine condylar facets (n=6/group), treated with OATS or crushed bone graft. 1.5 T MRI was performed 6 months after surgery using PD-weighted (w fat saturated (fs) fast spin echo (FSE), T1-w 2D, and 3D fs gradient echo (GE) sequences 30 min. after i.v. Gd-DTPA administration and passive joint exercise. The repair tissue was evaluated by two independent radiologists. The MR findings were compared to histology. RESULTS: In all cases, MRI and histologic grading correlated well and showed significant superior repair in OATS at 6 months (p<0.05), reproducing the original articular contour and a good subchondral restoration. FsT1-w3DGE proved most appropriate identifying characteristic post-operative findings: the OATS group demonstrated bone marrow edema at the donor site and the graft/host interface showed significant enhancement in indirect MR-arthrography, indicating fibrocartilage. After crushed bone graft, we found an irregular structure and significant contrast uptake, consistent with remnants of bone grafts surrounded by inflammatory tissue. CONCLUSION: Indirect MR-arthrography is an accurate, non-invasive monitoring tool following OATS and crushed bone graft as the MRI scoring and grading system allows a reliable evaluation of normal and pathological osteochondral repair with a high histologic correlation.
Zeitschriftentitel:
Eur J Radiol
Jahr:
2009
Band / Volume:
70
Heft / Issue:
1
Seitenangaben Beitrag:
155-64
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.ejrad.2008.01.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18289819
Print-ISSN:
0720-048X
TUM Einrichtung:
Fachgebiet Sportorthopädie (Prof. Imhoff)
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