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Title:

Enzyme-based assay for quantification of chlorpyrifos oxon in human plasma.

Document type:
Journal Article
Author(s):
Heilmair, R; Eyer, F; Eyer, P
Abstract:
Chlorpyrifos oxon (CPO) is the active metabolite of the pesticide chlorpyrifos that inhibits cholinesterases at high reaction rates. Chlorpyrifos is of major concern because it causes some ten thousand fatalities each year, mostly due to suicidal attempts. Notwithstanding, toxicokinetic studies on chlorpyrifos in humans are scarce and CPO has not been detected hitherto in human blood. Knowledge of the concentration and the time course of CPO in poisonings would be helpful to better design antido...     »
Journal title abbreviation:
Toxicol Lett
Year:
2008
Journal volume:
181
Journal issue:
1
Pages contribution:
19-24
Language:
eng
Fulltext / DOI:
doi:10.1016/j.toxlet.2008.06.868
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18655824
Print-ISSN:
0378-4274
TUM Institution:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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