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Title:

Seromucosal transport of intravenously administered carbamazepine is not enhanced by oral doses of activated charcoal in rats.

Document type:
Journal Article
Author(s):
Eyer, F; Jung, N; Neuberger, H; Witte, A; Poethko, T; Henke, J; Zilker, T
Abstract:
The fate of carbamazepine after intravenous injection in rats (n = 24) and the influence of activated charcoal on the kinetics was investigated. After randomization to four groups (n = 6, each), plasma concentration and the quantities of carbamazepine and metabolites excreted into bile, urine and intestine were determined using an in situ perfusion model of the small intestine (Ringer's solution) with or without orally administered activated charcoal (AC+; AC-) and with or without bile duct can...     »
Journal title abbreviation:
Basic Clin Pharmacol Toxicol
Year:
2008
Journal volume:
102
Journal issue:
3
Pages contribution:
337-46
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1742-7843.2007.00193.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18248517
Print-ISSN:
1742-7835
TUM Institution:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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