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Title:

Transplant acceptance-inducing cells as an immune-conditioning therapy in renal transplantation.

Document type:
Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't
Author(s):
Hutchinson, JA; Riquelme, P; Brem-Exner, BG; Schulze, M; Matthäi, M; Renders, L; Kunzendorf, U; Geissler, EK; Fändrich, F
Abstract:
The transplant acceptance-inducing cell (TAIC) is a type of immunoregulatory macrophage with the capacity to specifically dampen allogeneic rejection responses to a degree allowing safe minimization of conventional immunosuppressive therapy. In the first part of this report, the production and phenotype of the human TAIC is described. In the second part, an analysis is given of the TAIC-I clinical trial, in which 12 recipients of renal transplants from deceased donors were treated with donor-der...     »
Journal title abbreviation:
Transpl Int
Year:
2008
Journal volume:
21
Journal issue:
8
Pages contribution:
728-41
Fulltext / DOI:
doi:10.1111/j.1432-2277.2008.00680.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18573142
Print-ISSN:
0934-0874
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann)
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