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Titel:

Treatment of septic patients with an arginine-based endotoxin adsorber column improves hemodynamics and reduces oxidative stress: results of a feasibility study.

Dokumenttyp:
Clinical Trial; Journal Article; Article
Autor(en):
Umgelter, A; Reindl, W; Lutz, J; Kreymann, B; Ronco, C; Huber, W; Frank, H; Schmid, RM; Heemann, U
Abstract:
BACKGROUND: Mortality of severe sepsis and septic shock is unacceptably high. Adsorptive removal of endotoxin may interrupt the inflammatory cascade triggered by lipopolysaccharide. METHODS: Prospective feasibility study with plasma separation and adsorption (PSA) treatment using a novel arginine-coated adsorber column was performed in a tertiary care gastroenterological intensive care unit. RESULTS: 10 patients with severe sepsis/septic shock (median APACHE II score: 27, hospital mortality 40%)...     »
Zeitschriftentitel:
Blood Purif
Jahr:
2008
Band / Volume:
26
Heft / Issue:
4
Seitenangaben Beitrag:
333-9
Sprache:
eng
Volltext / DOI:
doi:10.1159/000132464
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18483452
Print-ISSN:
0253-5068
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann); II. Medizinische Klinik und Poliklinik (Gastroenterologie)
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