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Titel:

The cross-talk between NF-kappaB and HIF-1: further evidence for a significant liaison.

Dokumenttyp:
Comment; Journal Article
Autor(en):
Gorlach, A; Bonello, S
Abstract:
HIF-1 (hypoxia-inducible factor-1) has been shown to essentially control the cellular response to hypoxia. Hypoxia stabilizes the inducible alpha-subunit, preventing post-translational hydroxylation and subsequent degradation via the proteasome. In recent years, clear evidence has emerged that HIF-1alpha is also responsive to many stimuli under normoxic conditions, including thrombin, growth factors, vasoactive peptides, insulin, lipopolysaccharide and cytokines such as TNF-alpha (tumour necrosi...     »
Zeitschriftentitel:
Biochem J
Jahr:
2008
Band / Volume:
412
Heft / Issue:
3
Seitenangaben Beitrag:
e17-9
Sprache:
eng
Volltext / DOI:
doi:10.1042/BJ20080920
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18498249
Print-ISSN:
0264-6021
TUM Einrichtung:
Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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