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Title:

siRNA delivery by magnetofection.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Mykhaylyk, O; Zelphati, O; Rosenecker, J; Plank, C
Abstract:
Magnetofection is defined as the magnetically enhanced delivery of nucleic acids associated with magnetic nanoparticles and has been utilized to deliver synthetic siRNAs to cultured cells. Certain magnetic nanomaterials associate with siRNAs and are suitable for siRNA delivery, either alone or in combination with cationic polymers or cationic lipid enhancers; these complexes are targeted to the cell surface by application of a gradient magnetic field. In this review methods are described to exa...     »
Journal title abbreviation:
Curr Opin Mol Ther
Year:
2008
Journal volume:
10
Journal issue:
5
Pages contribution:
493-505
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18830925
Print-ISSN:
1464-8431
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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