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Titel:

Assessment of {alpha}v{beta}3 integrin expression after myocardial infarction by positron emission tomography.

Dokumenttyp:
Journal Article; Article
Autor(en):
Higuchi, T; Bengel, FM; Seidl, S; Watzlowik, P; Kessler, H; Hegenloh, R; Reder, S; Nekolla, SG; Wester, HJ; Schwaiger, M
Abstract:
AIMS: The purpose of this study was to determine the feasibility of a new positron emission tomography (PET) imaging approach using an (18)F-labelled alpha(v)beta(3) integrin antagonist ((18)F-Galacto-RGD) to monitor the integrin expression after myocardial infarction. METHODS AND RESULTS: Male Wister rats were subjected to 20 min transient left coronary artery occlusion followed by reperfusion. Autoradiographic analysis and in vivo PET imaging were used to determine myocardial (18)F-Galacto-RGD...     »
Zeitschriftentitel:
Cardiovasc Res
Jahr:
2008
Band / Volume:
78
Heft / Issue:
2
Seitenangaben Beitrag:
395-403
Sprache:
eng
Volltext / DOI:
doi:10.1093/cvr/cvn033
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18256073
Print-ISSN:
0008-6363
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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