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Document type:
Journal Article; Article 
Author(s):
Bayer, C; Schilling, D; Hoetzel, J; Egermann, HP; Zips, D; Yaromina, A; Geurts-Moespot, A; Sprague, LD; Sweep, F; Baumann, M; Molls, M; Adam, M 
Title:
PAI-1 levels predict response to fractionated irradiation in 10 human squamous cell carcinoma lines of the head and neck. 
Abstract:
BACKGROUND AND PURPOSE: To investigate the relationships between hypoxia, VEGF and components of the plasminogen activation system (PAS) and to determine their influence on local tumour control after fractionated radiotherapy. MATERIAL AND METHODS: Ten cell lines derived from human squamous cell carcinomas of the head and neck (SCCHN) were investigated in vitro and used to generate xenograft tumours. The pimonidazole hypoxic fraction in the total tumour area (pHF(tot)) was used to measure hypoxi...    »
 
Journal title abbreviation:
Radiother Oncol 
Year:
2008 
Journal volume:
86 
Journal issue:
Pages contribution:
361-8 
Language:
eng 
Print-ISSN:
0167-8140 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie